It is important to recognize that both older and younger patients can experience polypharmacy and be affected by the systemic and oral adverse events. Patients experiencing polypharmacy, and in the case of younger patients their parents/guardians, should be educated on the potential adverse effects.

With respect to oral health, more frequent dental visits and an increased focus on oral hygiene, diet, and prevention are essential for patients experiencing polypharmacy. Collaboration with medical professionals is also recommended to help optimize care.